Table 2 Cox proportional hazards regression model to estimate the risk of AD at the last visit

From: Dissecting the clinical and pathological prognosis of MCI patients who reverted to normal cognition: a longitudinal study

	Stable NC vs. Stable MCI			MCI Reverters vs. Stable MCI			MCI Reverters vs. Stable NC
	N	HR (95%CI)	p	N	HR (95%CI)	p	N	HR (95%CI)	p
Primary analysis
	571	0.091 (0.042, 0.198)	< 0.001	385	0.104 (0.033, 0.335)	< 0.001	390	1.522 (0.379, 6.108)	0.533
Subgroup analysis
APOE4 allele carrier	195	0.048 (0.011, 0.208)	< 0.001	145	0.062 (0.008, 0.456)	0.006	116	1.377 (0.110, 17.196)	0.804
APOE4 allele non-carrier	376	0.129 (0.050, 0.334)	< 0.001	240	0.163 (0.038, 0.698)	0.015	274	1.584 (0.300, 8.355)	0.588
Female	304	0.093 (0.032, 0.271)	< 0.001	239	0.054 (0.007, 0.395)	0.004	187	0.787 (0.084, 7.390)	0.834
Male	267	0.077 (0.025, 0.244)	< 0.001	164	0.172 (0.040, 0.748)	0.019	203	3.925 (0.611, 25.222)	0.150

Abbreviations: AD Alzheimer’s diseases, NC Normal cognition, MCI Mild cognitive impairment, HR Hazard ratios, CI Confidence interval, APOE Apolipoprotein E

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ISSN: 1741-7015

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