Table 1 Descriptive statistics of all cohorts
Cohort | UK Biobank | NESDA | ALSPAC mothers | ALSPAC partners |
|---|---|---|---|---|
N | 165747 | 904 | 9537 | 5235 |
Age in years at baseline (Mean, Range) | 56 (38–72) | 41 (18–65) | 29 (15–44) | 31 (16–65) |
Age in years at most recent follow-up (Mean, Range) | 66 (50–82) | 46 (21–72) | 48 (34–63) | 53 (38–82) |
Sex (n, % Female) | 92700 (56) | 582 (64) | 9537 (100) | 5235 (0) |
Ethnicity (n, % White or North-European descent) | 160861 (97) | 866 (96) | 9349 (98) | 5151 (98) |
Education (n, % University Degree) | 94735 (57) | 149 (16) | 1418 (15) | 1385 (26) |
Childhood maltreatment (n, % Yes) | 18996 (12) | 175 (20) | 1059 (11) | 466 (9) |
Comorbidity | ||||
 Unaffected (n, % Yes) | 134474 (81) | 694 (77) | 5308 (56) | 4059 (76) |
 Depression at most recent follow-up (n, % Yes) | 17145 (10) | 163 (18) | 728 (8) | 272 (5) |
 Cardiometabolic disease at most recent follow up (n, % Yes) | 11095 (7) | 32 (4) | 761 (8) | 499 (10) |
 Comorbidity at most recent follow-up (n, % Yes) | 1623 (1) | 15 (2) | 135 (1) | 38 (1) |
Alcohol intake (Mean, Range)a | 2 (0–4) | 3 (1–5) | 2 (1–6) | 3 (1–9) |
 Problematic alcohol intake (n, % Yes) | 38511 (23) | 241 (27) | 85 (1) | 353 (7) |
 Physical activity frequencyb or hours per weekc (Mean, Range) | 8 (0–63)c | 14 (0–63)c | 51 (1–217)d | 4 (1–6)b |
 Recommended physical activity (n, % Yes) | 135399 (82) | 715 (79) | 1500 (16) | 1606 (31) |
 Cigarettes per day (Mean, Range) | 1 (0–30) | 7 (0–72) | 3 (0–30) | 3 (0–30) |
 Smoker (n, % Yes) | 11765 (7) | 270 (30) | 2705 (28) | 1595 (31) |